Comprehensive Strategies for Managing COPD Exacerbations
An Internet CME Newsletter
April 2007

WELCOME

Chronic obstructive pulmonary disease (COPD) is a condition that affects at least 12 million US adults. It is the fourth leading cause of death in the United States, claiming 119,000 lives annually. Acute exacerbations of COPD are largely responsible for this high mortality rate. Moreover, acute exacerbations increase the risk for hospitalization and mortality and have significant negative effects on pulmonary function and quality of life. In addition to the toll they take on patients, COPD exacerbations are costly to society as a whole—accounting for 35% to 45% of total per capita COPD health care costs.

Clinicians need to know that prevention is the best method for reducing the morbidity and mortality associated with COPD exacerbations, and that early and effective intervention is necessary if prevention fails. Awareness of algorithms and guidelines, particularly those issued by the Global Initiative for Chronic Obstructive Lung Disease, may minimize the incidence of acute exacerbations of COPD and improve quality of life.

This newsletter reviews the key pharmacologic and nonpharmacologic components of preventing acute exacerbations of COPD—including patient self-management and increased adherence to therapy. It also details diagnosis and treatment of acute exacerbations of COPD, along with follow-up after resolution of an exacerbation.

I hope the information in this newsletter is useful to you and your patients. When you submit your posttest for certification, please also include your activity evaluation, as your responses will help us target future activities to your educational needs.

Sincerely,

Wisia Wedzicha, MD, Editor
Professor of Respiratory Medicine

University College London

London, England

Sponsorship and Support
Sponsored by Veritas Institute for Medical Education, Inc. Supported by an educational grant from Boehringer Ingelheim Pharmaceuticals Inc and Pfizer Inc.

Method of Participation
Complete the Pretest, read this newsletter, complete the Posttest, Activity Evaluation, and Request for Credit Form.  To receive your CME certificate immediately, you must receive a Posttest score of 70% or higher. This activity is provided free of charge to participants.

Intended Audience
Pulmonologists

Effective Dates
April 2007 to March 31, 2008

Accreditation/Designation of Credit Statements
Veritas Institute for Medical Education, Inc. is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Veritas Institute for Medical Education, Inc. designates this educational activity for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Financial Disclosure Statements
In accordance with the ACCME’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Disclosures are as follows:

Wisia Wedzicha, MD: AstraZeneca Pharmaceuticals LP (speaker), Boehringer Ingelheim Pharmaceuticals Inc (speaker), GlaxoSmithKline (advisory board and speaker).

Richard Casaburi, PhD, MD: Altana Pharma AG (research grant), AstraZeneca Pharmaceuticals LP (advisory board), Boehringer Ingelheim Pharmaceuticals Inc (speaker, research grant, advisory board), Forest Laboratories Inc (consultant), Pfizer Inc (speaker, advisory board), Roche Pharmaceuticals (research grant).

The staff of Veritas Institute for Medical Education, Inc. has nothing to disclose.

Unlabeled Use Disclosure Statement
Participants are advised that this CME activity will contain references to the unlabeled/unapproved/investigational uses of drugs to treat acute exacerbations of COPD.

Disclaimer
The opinions expressed in this activity are those of the faculty and do not necessarily reflect those of Veritas Institute for Medical Education, Inc., Boehringer Ingelheim Pharmaceuticals Inc, or Pfizer Inc. Please consult the appropriate package insert for full prescribing information on all drug therapies discussed.

Editorial Board

Editor

Wisia Wedzicha, MD
Professor of Respiratory Medicine

University College London

London, England

 

Faculty Reviewer

Richard Casaburi, PhD, MD

Associate Chief of Research

Division of Respiratory and Critical Care Physiology and Medicine

Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center

Torrance, California

Copyright © 2007 Veritas Institute for Medical Education, Inc. All rights reserved.

LEARNING OBJECTIVES

1.      You will be able to identify and explain the risk factors for and pathophysiology of acute exacerbations of COPD.

2.      Using current consensus guidelines, you will be able to accurately diagnose acute exacerbations of COPD in patients presenting with relevant symptoms, regardless of whether they have had a previous diagnosis of COPD.

3.      You will be able to assess effective pharmacologic and nonpharmacologic therapies to treat COPD patients with acute exacerbations, in both the outpatient and inpatient settings.

4.      You will be able to integrate pharmacologic and nonpharmacologic approaches to help prevent exacerbations and minimize the chances of recurrence.

 

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Please answer this brief pretest before you start this activity. Your answer will help us gauge your understanding of this subject matter.

To what extent do you agree/disagree with the following statements?

Individualized action plans are helpful in reducing patient concerns but do not have a significant impact on COPD exacerbations.

Long-acting bronchodilators reduce the frequency of COPD exacerbations.


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